PLENHYAGE XL Medium (1x2ml)
The lowest price of the product zł245.00 in day 31.01.2026
Lowest price in the last 30 days: zł245.00
Plenhyage XL Medium is a sterile, viscoelastic Class III medical device in the form of an injectable solution, based on polymerized polynucleotides (PDRN) at a concentration of 20 mg/ml. The preparation is intended for the biomechanical restructuring of the dermis and the intensive bioregeneration of the extracellular matrix (ECM). Due to the higher concentration of the active ingredient, the device provides strong structural support for tissues with visible signs of aging, loss of volume, and scarring.
mechanism of action
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induction of fibroblast proliferation: polynucleotides activate A2A adenosine receptors, which stimulates fibroblasts to increase the production of type I collagen and elastin, leading to the physical restoration of dermal density and structure
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hydrodynamic stabilization of the ecm: polymerized polynucleotide chains exhibit a high capacity for iso-osmotic water binding, ensuring deep and long-term tissue hydration and improvement of tissue volume
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protection against oxidative stress: the device acts as a mechanical scavenger of free radicals, neutralizing reactive oxygen species generated by uv radiation and metabolic stress, thereby slowing down the degradation of structural fibers
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mechanical reduction of scars and wrinkles: the preparation supports the correct reorientation of collagen fibers in scarred areas and mechanically fills deeper skin folds, such as cheek and perioral wrinkles
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optimization of the cellular microenvironment: by providing nucleotides and nucleosides, the device supports the physiological repair processes of damaged cells, restoring skin tension and elasticity
indications and intended use
The device is intended for administration via intradermal injection by authorized medical personnel to:
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correction of medium and deep wrinkles: provide mechanical smoothing of wrinkles around the mouth and on the cheeks
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biorestructuring and lifting: restore lost firmness, tension, and volume of the tissues on the face, neck, and décolletage
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reduction of structural defects: provide physical reduction of the visibility of scars and skin texture irregularities
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intensive revitalization of aging skin: provide mechanical support for repair processes in skin with reduced regenerative potential
application areas
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face (particularly areas with volume loss and deep wrinkles)
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neck and décolletage
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other body areas requiring scar correction or restructuring
composition
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Polymerized Polynucleotides (PDRN): 40 mg / 2 ml (20 mg/ml concentration)
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Water for injection, buffering system: physiological carrier
technical information
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form: pre-filled syringe with viscoelastic solution
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application site: dermis (middle and deep layers)
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injection parameters: recommended 30G 13 mm needle
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technique: linear-retrograde, fanning, or micro-depots (depending on clinical indications)
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dosage: according to individual medical recommendations, adjusted to the severity of tissue changes
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volume: 2 ml
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package contents: 1 pre-filled syringe, 2 needles (30G 13 mm)
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PRE-FILLED SYRINGE |
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The product may only be used by professionals. By making a purchase, you declare that you are a doctor or cosmetologist trained in aesthetic medicine. |
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