The lowest price of the product zł255.00 in day 20.01.2026
Nucleofill Medium is a sterile, biocompatible Class III medical device in the form of a viscoelastic gel based on polynucleotides (sodium DNA salt). The preparation is intended for deep biostimulation and restructuring of the dermis. It operates through a triple mechanism: receptor-based activation of fibroblasts, intensive hydration of the extracellular matrix structures, and neutralization of free radicals. The device provides physical correction of tissue deficits, improvement of skin biomechanical parameters, and prophylaxis against involutional changes.
mechanism of action
receptor stimulation of fibroblasts: polynucleotides activate specific membrane receptors (a2), stimulating cells for the biosynthesis of type i collagen and elastin, leading to physiological lifting and tissue densification
iso-osmotic water retention: the high hydrophilic capacity of polynucleotides allows for long-term water binding in the intercellular spaces, providing stable hydration of the deep skin layers
antioxidant protection: the chemical structure of polynucleotides allows for the scavenging of free radicals and inhibition of oxidative stress, protecting the ecm from enzymatic degradation
mechanical structural support: due to its optimal viscosity (28–43 pa·s), the preparation physically fills skin deficits, modeling facial contours and improving soft tissue volume
regulation of tissue homeostasis: the device creates optimal physiological conditions for repair processes, supporting the regeneration of scars and stretch marks
indications and intended use
The device is intended for deep-intradermal implantation by authorized medical personnel to:
biostimulation of skin with reduced tension: improvement of elasticity and prevention of wrinkle formation (particularly in patients with early signs of aging)
treatment of dehydration and hypoxia: revitalization of hypoxic skin exposed to oxidative stress and dryness
correction of structural defects: filling wrinkles, improving volume, and modeling the facial oval
scar tissue therapy: supporting regeneration within stretch marks and atrophic scars
biomechanical lifting: improving tissue cohesion in areas requiring elevation
application areas
face (including the 5-point bio-aesthetic technique)
neck and décolletage
body (areas with scars or stretch marks)
composition
Polynucleotide gel (sodium DNA salt): 20 mg/ml
Physicochemical characteristics: molecular weight 50-100 kDa; pH 6.8–7.2; viscosity 28–43 Pa·s
technical information
form: pre-filled syringe with sterile gel
application site: deep layer of the dermis or subcutaneous layers
injection parameters: 30G x 13 mm needle
injection techniques: 5-point technique, linear retrograde technique, multi-injection (needle mesotherapy)
dosage: individual, usually 1.5 ml per area; do not exceed 6 syringes in a full therapeutic cycle
treatment cycle: a series of 4 treatments at 2–4 week intervals
volume: 1.5 ml
package contents: 1 pre-filled syringe
 |
PRE-FILLED SYRINGE |
|
 |
The product may only be used by professionals. By making a purchase, you declare that you are a doctor or cosmetologist trained in aesthetic medicine. |
|
Dear Customer
The online store www.centerfillers.com is intended for professionals, people with education in the field of medicine, aesthetic medicine and for entrepreneurs interested in the store's products in connection with their business activity.
By going to the website www.centerfillers.com, I declare that I am aware that the content on the website is intended only for professionals and I am a person with education in the field of aesthetic medicine, or I am an entrepreneur interested in the offer as part of my business activity.
I confirmLeave this page
Cookies
